I am BRCA1 possitive fighting ovarian cancer for the past 8 years.  This is wonderful news to me and I will speak with my oncologists about joining the study.  What wonderful news!

Like the PARP inhibitors which await FDA approval for breast and ovarian cancers, an innovative liver cancer medication is nearing commercialization.
On the subject of break-through cancer drugs, Celsion, a leading-edge BioPharma company, has recently received Orphan Drug Status designation from the FDA for its medication known as Thermodox. Thermodox is a new formulation of the established cancer medication, doxirubicin initially targeting Liver Cancer Tumors. Utilizing peptide ligand technology the nano-encapsulated Thermodox is delivered through the blood stream exactly to the tumor's sight. Then microwave heat at the modest level of not more than 104 degrees fahrenheit is directed precisely at the encapsulation adjacent to the tumor releasing the thermodox and destroying the tumor. This procedure is currently investigating the most desireable dosage and should be ready for an NDA submission in the near future. A non-invasive treatment for liver tumors has been unavailable until now and most tumors have proven fatal unless the patient could obtain and endure a liver transplant.

I was very interested in your report on PARP inhibitors tonight. It seems to work much like a new drug by Genta called Genasense. It might make a good story because Genta has been one of those companies that has been tortured almost to death by the FDA and horrible stock manipulation. So many good drugs die in this way before anyone can buy them. They are, after years and years, about to get approval this Fall--maybe. Similar outcomes to PARP but only three months away.

 As I watched Brian Williams' report on PARP inhibitors tonight, I was dismayed that no credit was given to the drug industry scientists who discovered the drugs that the academics were interviewed about.  Who made the breakthrough?  Not the professors who were interviewed.  What is wrong with naming the companies which discover and develop life-saving new drugs?  My sense is that there is no shortage of negative reporting about drug companies.

My name is Barbara W.and I was diagnosed with Ovarian Ca.I had total hysterectomy,appendectomy and peritoneal lining removed on 11/28/2006. TAXOL/CARBOPLATIN started on 12/12/2006 for 4mos.I had 4mos.remission? Then started on TOPOTECAN for 3 mos. with little to no response.I had 12mos of DOXIL- * CLEARANCE noted. OFF for 5 mos and now back on DOXIL(PETSCAN). Need PARP?

This report is wonderful news. As a carrier of the BRCA 1 Gene, and a survivor of Ovarian and Breast Cancer, if not for me, but my daughter and son. At last there is possible a cure for cancer.

How do I know I qualify for this drug? I am a cancer patient. Breast cancer of the sternum mets to lymph nodes & lung. I am currently on Tykerb, Herceptin & Zometa. Your help is very much appreciated

my name is donna gonzales and i would like to know more about this drug please and how do i go about seeing if i can take it i have had ovain cancer and i have had it since 2005 right now they are giving me a pill called TAMOXIFEN 20 mg one time a day i would like to see if i would be able to take the pills u all are talking about so if u could please let me know    donna gonzale

Trying to find parp inhibitors for brother with terminal prostate cancer

What is the status of PARP research regarding regarding prostate cancer that is not genetically linked.  Cathy

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