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Bionic eye sheds light on blindness

Posted: Tuesday, June 16, 2009 4:48 PM by Daily Nightly Editor

By Robert Bazell, NBC News chief science correspondent

 

On Tuesday night we'll report on a research project that is literally allowing blind people to see again. Even though the project has been in progress for two decades, supported by the Department of Energy--first at Johns Hopkins now at the University of Southern California--the results have been limited. But given the enormous challenges, they are still impressive. 

People who were totally blind could at first perceive dots of light that allowed them to avoid bumping into objects. Now, as the system is progressing, they can begin to make out the outlines of faces and other large objects.
 
The system works by taking the signal from a tiny camera on a pair of sunglasses, which then runs through wires that are implanted on the surface of the retina.  These electrodes stimulate the retinal cells to send signals to the brain that are perceived as light. 

You can read about the project in detail including diagrams of how it works here: http://www.doheny.org/research/pdfs/arnvol1no1.pdf


As Dr. Mark Humayan, the project leader, explained to me, the challenges involve both software and hardware.  Even though we often use metaphors of physical objects like video cameras and computers to try to understand how body parts like eyes and brains work, the "software" code is very different for our body than it is for electronics.  Matching the codes has taken almost two decades. 
 
The hardware problem is that electronics are dry, while our bodies are moist and salty. Getting the electric leads to work in the eye is "like throwing a cell phone in the ocean," according to Humayan.
 
For now, the patient must turn so that the camera faces whatever he or she is trying to see. But Armand R. Tanguay, Jr., an electronics engineer, has designed a tiny video camera that will literally fit into the front lens of the eye, allowing the person to just move their eyes to see.
 
Currently the project treats only people with the blinding condition retinitis pigmentosa.  In the future, the researchers  plan to move on to other conditions, including macular degeneration. The waiting list for those wishing to become research subjects is long, but anyone interested should call: (818) 833-5000.

 

More info on "bionic eyes":
http://bmes-erc.usc.edu/research

http://artificialretina.energy.gov/
http://www.usc.edu/schools/medicine/departments/ophthalmology/index.html
http://www.doheny.org/
http://www.2-sight.com/

 

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Comments

What wonderful news of a beginning to allow blindness to be healed. Thank you Robert for telling the story.
I wonder if this would work for people who have Septo Optic Dysplasia, where the optic nerves are underdeveloped or not present?
Is there a possibility that this new procedure could benefit a person with mitrochondrial myopathy?  Please excuse me if I have misspelled this condition.
hello. my daughter[Pattie] was born in 1970 the dr.s said her nerves didnot develope from the brain to the eye. and that their were like millions of nerves inside nerves to the eye. she has been blind since birth. I was just wondering if or will their ever be a miracle dr. to figure this out. It would be a miracle for us.                 thank's   Pat
My son is 2 years old and have atrophie on the optical nerve (he is blind). He also have other neurological problem named "esquizencefalia de labio aberto" on the left side of the brain. We have collected the cells when he was born.

Is there any research that coud help him see?
Is this available to the public yet? My mother has macular degeneration & I feel like this would help her. She lost her vision 5 years ago. This would truely be a miracle.
I am so thankful that people who are blind might have a way to see again i have a child who has been blind since birth he has had many eye cornea transplants and have failed i am hoping someday he will be able to see more.
I can see that it will not be much help unless someone has a retina intact.  But I am encouraged that there is a place in California which can deal with unusual problems of eye damage.  I hope that they can restore some sight in the one eye with a retina, for the 4 year old in Bakersfield, who has this horific injury at the hands of his father.
BIONIC EYE SHEDS LIGHT ON BLINDNESS
who ever did this thankyou .retinitis pigmentosa is what i have and been dealing with  since 2003 ..what type of cure  In the future, the researchers  plan to do and will it help me see better in the dark and help my colorblindness.I do need a cure 4 me..So how do i  become a research subjects.
My name is Christine McElwee.  I have a 29 year old daughter who has lost almost all her sight due to a rare disease called Erdheim Chester Disease.  I would like more information on the Bionic Eye and if there is a chance it could help her regain any of her sight.
Thank you.
Great story. I hope blind people can see it on your web site which is not too blind-friendly.
My wife has suffered a stroke and as a result has been blind for three years.  She can see bright light and some movement.  Is there a possibility that this might be of some help to her?
my daughter lost her sight to cancer of the retina. any way this could help her?
my husband has had wet and now dry macular degeneration in both eyes over the past twenty years and is now blind.  could the bionic eyeglasses (and the future camera transplant) be used to restore sight with this condition?  also, when will the glasses be available for purchase and what would be the approximate cost?
This is powerful message with hope for many people.  Our 17 year old granddaughter is blind but has always known this day would come.  She lost her sight completely about three years ago.  While this is the firs step, I believe she will see again.  Thank you to all the dedicated researchers who have given so much to so any.
I became blind about 4 years ago when I was diagnosed with Giant Cell Arteritis where my optic nerve was affected.  One eye is blind 100% and the other about 90% and I can only see periphial vision.  Is there anything that you know of that could help me.  Please advise.  Thank you.
great news! I'm going to forward this article on to some of my blind friends at the South Carolina Commi8ssion for the Blind; they'd love to know there's this kind of research being done and signs of HOPE for the future. Thanks much for this and I'll call t6hat 800#  to get myself on the waiting list. I've got macular degeneration in one eye at present and the other's  not too swift either. I'd gladly offer myself as a guinea pig at a trial or whatever.
Again, a million thanks. Marilyn DeLaunay. Winnsboro, SC
My husband lost his eyesight about 8 years ago because of diabetes.  We were wondering if this bionic eye would help him and also if there was any way to find out if he could be a test subject
I am slowly going blind to this degenerative condition known as retinitis pigmentosa, as though this wonderful reseach will probably not be completed in time to help me, I hope it will progress quicky so it will be able to help my young teenage daughter who also has this awful life altering condition. Thank you so much Mr. Bazell for bringing RP to the attnetion of the general public, as most people know nothing about it. Education and Media Attention are the key to the money necessary for research such as this that are is so greatly needed for projects such this one to continue!!
My daughter had a detached retina in 2005 after a severe attack of meningitis.  This is good news Robert - please let me how I can get my daughter to have her sight restored.  My daughter is 38 years - the blindness has left her devasted.
my son completely lost his sight 18years ago, because of tumor.
at that time his optic nerve was destroyed by tumor.
please let me know,this research help him?
Hello, This is amazing!...I have a 7 year old little boy who is diagnosed with optic displasia...where is optic nerve doesnt connect to his eyes...I have been researching everywhere for a possilbe cure or...a miracle, are there any studies being done on this?
My husband lost his eyesight in one eye after heart surgery-the drop in blood pressure caused Optic Neuropothy-- He had already lost most of his vision in the other eye.  He wants so much to participate in any study available for Optic Neuropothy- Is this part of your study?

Carlita
I have a client who lost her eyesight. She can see some colors and shadows, according to her. What can we do for her, if anything. Can some one let me know. Thanks.

Abraham


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